Design Considerations in Embedded Pragmatic Trials: Separating Rigor from Idolatry

Gregory Simon, MD, MPH | September 12, 2023: This presentation will consider specific considerations in the design and implementation of embedded pragmatic trials, including: eligibility criteria, unit of allocation, method of allocation, standardization of “active” interventions, standardization of “control” interventions, blinding, and analytic strategy. For each of these design decisions, investigators must focus on the…

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Innovating Substance Use Disorder Treatment at Scale

Jeffrey De Flavio, MD | September 26, 2023: Across medicine clinical innovations take years to disseminate widely into practice, while some best practices in addiction medicine fail to ever gain widespread adoption. This presentation describes two private medical practices (Groups Recover Together and Affect Therapeutics) which have brought underutilized and evidence-based interventions to scale across…

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Proposing and Applying the Observational-Implementation Hybrid Approach

Justin Knox, PhD, MPH | October 10, 2023: We recently proposed the observational-implementation hybrid approach, or the incorporation of implementation science elements into observational studies in order to collect information that will allow for anticipation, estimation, and/or inference about the effects of interventions and implementation strategies. We describe this approach, including examples of how we…

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The Economics of Efficiency in Implementation Science

Todd Wagner, PhD | May 9, 2023: Efficiency is upheld as a cornerstone of high-quality care. Unfortunately, the term efficiency is used in different contexts, creating substantial confusion about what it means. In this talk, I define efficiency as it relates to the delivery of health care. I then review different frameworks for measuring it…

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Development of an integrated implementation determinant framework for shared learning to promote health equity

Lilian Perez, PhD and James Merle, PhD | May 2, 2023: As evidence-based innovations (EBIs) are translated into clinical and community settings, implementation determinant frameworks can help understand the factors that impede or facilitate implementation outcomes. Use of different frameworks across implementation initiatives can impede shared learning. To develop a framework for shared learning in…

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Bridging policy research and implementation science

Beth McGinty, PhD | April 25, 2023: Policy implementation is a key but often-ignored aspect of policy effectiveness. Public policy research typically considers the effects of having versus not having a policy on outcomes, without considering whether and how the policy was implemented – even though the effects of policies on their intended outcome depend…

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Prosocial Behaviors as a Marker of Health and Enhancer of Well-Being

Gustavo Carlo, PhD | April 18, 2023: Drawing upon a strengths-based, cultural assets perspective, I will present evidence on the growth properties of prosocial behaviors and assert the need to incorporate prosocial behaviors as a marker of health and well being. The presentation will focus on risk and protective correlates and consequences of prosocial behaviors…

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A cost-effectiveness analysis of telemedicine and mobile health interventions to support continuing care

Andrew Quanbeck, PhD | April 11, 2023: This presentation reports the cost-effectiveness analysis from a fully powered randomized clinical trial that featured a head-to-head comparison between telemedicine and digital health interventions for providing continuing care for patients with alcohol use disorder. A telemedicine intervention (telephone monitoring and counseling: TMC) and a mobile health intervention (Alcohol…

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