Articles (Publications)
Tracking Implementation Determinants Over Time Using the IFASIS: Multi-Site Analysis of Opioid Treatment Programs Implementing a Digital Contingency Management Platform
Background: Contingency management (CM) is the most effective treatment for stimulant use, but is underutilized due to implementation challenges. Digital CM platforms have shown promise in addressing barriers to implementation, but there is limited understanding of factors impacting delivery of a digital CM platform over time. The goal of this longitudinal study was to measure…
Read MoreChallenges With Buprenorphine Initiation in the Fentanyl Era—Adapting Effectively to the Moment
Buprenorphine is a cornerstone medication for opioid use disorder (OUD) but carries a known risk of precipitated withdrawal (PW) during initiation, a concern that appears to be increasing in the era of nonpharmaceutical fentanyl (NPF). Kawasaki and colleagues report findings from a 2023–2024 nationally representative survey of 396 US buprenorphine prescribers examining challenges with buprenorphine…
Read MoreImplementation Outcomes Included in NIDA Clinical Trials Network (CTN) Studies: A Systematic Review of Studies Conducted Over 20 Years
The National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN) has supported clinical trials of substance use disorder (SUD) interventions for 25 years. This review describes the use of implementation outcomes across CTN trials, characterizes outcomes included, and identifies gaps and potential opportunities to strengthen implementation research within the CTN and the field of…
Read MoreIntegrating Implementation Outcomes into Effectiveness Studies: A Practical Guide for Clinical Interventionists
Designing effectiveness studies with implementation in mind can allow interventionists to translate their research into real-world practice. Implementation outcomes measure how much and how well a particular intervention was implemented and can provide valuable insights into any heterogeneity in effectiveness outcomes. As part of the National Institutes of Health’s (NIH) Helping to End Addiction Long-term®…
Read MoreFrom Glitter to Gold: Recommendations for Effective Dashboards from Design through Sustainment
Dashboards—tools that compile and summarize key performance data—have become increasingly utilized for supporting data organization and decision-making processes across various fields, such as business, economics, healthcare, and policy. The dashboard’s impact is dependent on its use by the individuals for whom it was designed. Yet, few studies measure dashboard use, and of those that do,…
Read MoreUsing the IFASIS (Inventory of Factors Affecting Successful Implementation and Sustainment) to Advance Context-Specific and Generalizable Knowledge of Implementation Determinants: Case Study of a Digital Contingency Management Platform
Background: Contingency management (CM) is the most effective treatment for stimulant use disorder but is underutilized by opioid treatment programs (OTPs) despite the high prevalence of stimulant use in this setting. As part of a state-wide initiative, we piloted a novel assessment, the Inventory of Factors Affecting Successful Implementation and Sustainment (IFASIS), to examine determinants…
Read MoreA Pragmatic Measure of Context at the Organizational Level: The Inventory of Factors Affecting Successful Implementation and Sustainment (IFASIS)
Background: Successful implementation and sustainment of interventions is heavily influenced by context. Yet the complexity and dynamic nature of context make it challenging to connect and translate findings across implementation efforts. Existing methods to assess context are typically qualitative, limiting potential replicability and utility. Existing quantitative measures and the siloed nature of implementation efforts limit…
Read MoreSystemic Barriers and Stigma: Healthcare Provider Perspectives on Perinatal and Neonatal Care in the Fentanyl Crisis
The rise in fentanyl use during pregnancy has introduced new and complex challenges in caring for women with opioid use disorders (OUD) and their infants diagnosed with neonatal abstinence syndrome or neonatal opioid withdrawal syndrome (NAS/NOWS). Despite the increasing prevalence of opioid-affected mother-infant dyads, limited research exists on healthcare providers’ perspectives regarding fentanyl’s impact on…
Read MoreUnderstanding Inequitable Healthcare: Methodological Approaches, Challenges, and Opportunities
This paper considers methodological approaches that can help better understand inequity in healthcare, focusing on five key domains: availability, patient-centeredness, access, effectiveness, and implementation. We present conceptual definitions of each of these domains, example research questions pertaining to inequity in each domain, and methodological approaches that can contribute to research about health inequities. We discuss…
Read MoreRollout Trial Designs in Implementation Research are Often Necessary and Sometimes Preferred
Background: Rollout designs, which include stepped wedge designs, are defined by staggered implementation of new or alternative programs or services. Critiques of stepped wedge and other rollout designs have raised concerns regarding the confounding of true implementation or program effects with unrelated, global changes in service delivery, with some recommending they only be used when…
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