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Implementation Outcomes Included in NIDA Clinical Trials Network (CTN) Studies: A Systematic Review of Studies Conducted Over 20 Years
Year Published: 2025
Authors: Gonzalez, S. T., Horigian, V. E., Cheng, H., Hagedorn, H. J., Shmueli-Blumberg, D., Campbell, C. I., Lin, C., Rogers, E., Baloh, J., Hilton, R., Vena, A., McNeely, J., & Glass, J. E.
The National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN) has supported clinical trials of substance use disorder (SUD) interventions for 25 years. This review describes the use of implementation outcomes across CTN trials, characterizes outcomes included, and identifies gaps and potential opportunities to strengthen implementation research within the CTN and the field of SUD treatment.